![]() ![]() ![]() After propensity score matching, 6 pairs of patients were selected. In the well-matched cohort, CCL demonstrated significantly improved recurrence-free survival (RFS) ( P = 0.047) compared with ICL no significant differences were noted for overall survival (OS), operation time, blood loss and morbidity rate. A total of 227 patients from nine eligible studies and ours were involved in the systematic review. ![]() Keywords: hepatocellular carcinoma, caudate lobe, surgery, outcomes, meta-analysis Meta-analysis revealed that CCL provided better RFS (hazard ratio 0.54, 95% confidence interval 0.31– 0.92) than ICL no significant differences were observed in OS, operation time, blood loss and morbidity rate.Ĭonclusion: CCL confers superior RFS over ICL without compromise of perioperative outcomes and should be prioritized for patients with caudate HCC when feasible, especially for those with large-sized tumors. Hepatocellular carcinoma (HCC) is the most frequent primary liver malignancy and ranks sixth most common malignancy, with an increasing incidence worldwide. 1–3 Over the past decade, advances in surgical techniques, patient selection, and perioperative management have significantly reduced surgical mortality to below 3% at specialized hepatobiliary centers.ġ, 2 Surgical resection is considered to be the mainstay of potentially curative therapy for patients with localized HCC and preserved liver function. ![]()
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